Surveys of infectious disease experts aim to predict COVID-19’s toll | Science

Experts have forecasted rising numbers of U.S. COVID-19 cases as hospitals such as Mount Sinai South Nassau scramble to respond.

Jeffrey Basinger/Newsday via Getty Images

Sciences COVID-19 reporting is supported by the Pulitzer Center.

Statistical models of infectious disease are vital for understanding where the COVID-19 pandemic is headed. But their predictive power can be limited by sparse data and rapidly changing circumstances.

A useful complement to numerical models is forecasts made by experts using their informed judgment, says Tom McAndrew, a biostatistics postdoctoral researcher at the University of Massachusetts, Amherst. Each week since February, he and his faculty adviser, Nicholas Reich, have been surveying about 20 experts in public health and infectious disease, asking for their best estimates of future COVID-19 cases, hospitalizations, and deaths.

In last week’s survey, the specialists predicted that total U.S. deaths from COVID-19 will rise substantially in coming weeks; on average, they estimated that in the most likely scenario, the number of deaths will reach 45,157 on 1 May and 74,631 on 1 June.

The experts’ understanding of the dynamics of disease outbreaks informs their estimates, McAndrew says, much as weather forecasters craft predictions based on data and experience.

An inspiration for the effort is the Good Judgment Project, launched by psychologists at the University of Pennsylvania in 2011. It studied ways to improve forecasting using crowdsourcing; its team won competitions sponsored by an organization funded by U.S. spy agencies—the U.S. Intelligence Advanced Research Projects Activity—to accurately predict geopolitical events, such as the likelihood of chemical weapons inspections in Syria. The project “ended up identifying ‘superforecasters,’ those who had an uncanny ability to make very accurate predictions,” McAndrew says.

He notes that, in the first surveys of disease experts he conducted, the consensus predictions of the number of confirmed U.S. cases were lower than those actually reported later. But as the pandemic has expanded, McAndrew says, the forecasts made by the experts have become increasingle accurate.

On a hopeful note, the group forecasted last week that the United States will reach its peak number of monthly deaths no later than April.

Judgment calls

In a survey last week, 19 disease modelers offered a range of estimates for future COVID-19 death totals in the United States.

50,000Smallest number of deathsBy 1 May1 June100,000150,000200,000250,000300,000350,000400,000By 1 May1 JuneMost likely number of deathsBy 1 May1 JuneLargest number of deaths

Graphic: N. DESAI/SCIENCE; DATA: THOMAS MCANDREW/UNIVERSITY OF MASSACHUSETTS, AMHERST

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